Nobel Prize for Medicine awarded to trio who discovered how cells sense oxygen

FAN Editor

Three scientists have been announced as the winners of the 2019 Nobel Prize in Physiology or Medicine for discovering how cells “sense and adapt to oxygen availability,” the Nobel Committee announced Monday.

William G. Kaelin, Jr, Peter J. Ratcliffe and Gregg L. Semenza will equally share the 9 million kronor ($918,000) cash award.

BREAKING NEWS:
The 2019 #NobelPrize in Physiology or Medicine has been awarded jointly to William G. Kaelin Jr, Sir Peter J. Ratcliffe and Gregg L. Semenza “for their discoveries of how cells sense and adapt to oxygen availability.” pic.twitter.com/6m2LJclOoL

The Karolinska Institute said that the discoveries made by the three men “have fundamental importance for physiology and have paved the way for promising new strategies to fight anemia, cancer and many other diseases.”

Furthermore, the scientists “revealed the mechanism for one of life’s most essential adaptive processes,” according to the institute.

Kaelin works at Harvard, Semenza is at Johns Hopkins University and Ratcliffe works at the Francis Crick Institute in Britain, according to The Associated Press.

While humans have long understood why oxygen is important, it wasn’t clear how cells adapt to changes in oxygen.

The three scientists discovered how the body’s cells sense and change in response to different oxygen levels, which is important since oxygen is a critical factor in a number of diseases.

“Grant proposal deadlines wait for no-one!”

This year’s prize marks the 110th prize in medicine awarded since 1901.

Last year’s Nobel Prize in Medicine was awarded to James Allison and Tusuki Honjo for their work on immunotherapy, a method of harnessing the body’s immune system to fight cancer.

Nobel prizes in chemistry, physics and literature will be announced this week, with the most famous prize, the Nobel Peace Prize, announced Friday.

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