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Emergency personnel responded at about midnight to the area near the intersection of Third and South streets, Philadelphia Police said.
Officers arrived at the scene and saw a man fire into a crowd of people, prompting an officer to shoot three times, police said. Police recovered a weapon at the scene, but have not made an arrest, officials said.
Seven victims were transported to Thomas Jefferson University Hospital with injuries from the shooting, a hospital spokesperson said. One was reported dead on arrival and four others were in stable condition, the hospital said.
Police said other victims were transported to two additional area hospitals.
This is a developing story. Please check back for updates.